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Can saving the meniscus save knees from osteoarthritis?
NCT ID NCT07079254
First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time
Summary
This study follows 300 people with a specific type of knee injury called a displaced bucket-handle meniscus tear, which can lock the knee and damage the joint. Researchers will compare two surgical approaches: repairing the torn meniscus with stitches versus removing the damaged part. The goal is to see which approach better preserves knee function and reduces the risk of early knee osteoarthritis over 10 years, and to identify factors like age and timing of surgery that influence healing.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Meniscus suture (surgical repair) versus partial meniscectomy (surgical removal of the torn part)
- What this could lead to
- If successful, this could identify which patients benefit most from meniscus repair, potentially preserving more knees and reducing long-term osteoarthritis risk.
- What could go wrong
- This is an observational study, so it cannot prove cause and effect. Repair may fail in 20-30% of cases, requiring reoperation, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 300 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2023
- Expected to finish
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Dec 2045
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients who present to the emergency department or the orthopaedic outpatient clinics at our hospitals with a knee extension deficit after trauma, with a clinically suspected bucket-handle meniscus rupture, are referred to a magnetic resonance imaging (MRI) within a week. Patients with a bucket-handle tear on the MRI, and no younger than 15 years, will be invited to participate in the study. Recruitment takes place at the outpatient clinic at the orthopaedic department at Skåne University Hospital in Malmö and the orthopaedic department at Hässleholm hospital.
- Ages
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15 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 15 years or above. * Displaced longitudinal bucket-handle tear including the posterior horn on MRI and a knee extension deficit. Exclusion Criteria: * Patient younger than 15 years. * Insufficient knowledge of the Swedish language. * Per-operative findings including a bucket-handle rupture in combination with a complete radial rupture
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Region Skåne, Orthopaedic department Kristianstad/Hässleholm
RECRUITINGHässleholm, Skåne County, Sweden
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Region Skåne, Skåne University Hospital
RECRUITINGMalmö, Skåne County, Sweden
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