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Can saving the meniscus save knees from osteoarthritis?

NCT ID NCT07079254

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This study follows 300 people with a specific type of knee injury called a displaced bucket-handle meniscus tear, which can lock the knee and damage the joint. Researchers will compare two surgical approaches: repairing the torn meniscus with stitches versus removing the damaged part. The goal is to see which approach better preserves knee function and reduces the risk of early knee osteoarthritis over 10 years, and to identify factors like age and timing of surgery that influence healing.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Meniscus suture (surgical repair) versus partial meniscectomy (surgical removal of the torn part)
What this could lead to
If successful, this could identify which patients benefit most from meniscus repair, potentially preserving more knees and reducing long-term osteoarthritis risk.
What could go wrong
This is an observational study, so it cannot prove cause and effect. Repair may fail in 20-30% of cases, requiring reoperation, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 300 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2023

Expected to finish

Dec 2045

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients who present to the emergency department or the orthopaedic outpatient clinics at our hospitals with a knee extension deficit after trauma, with a clinically suspected bucket-handle meniscus rupture, are referred to a magnetic resonance imaging (MRI) within a week. Patients with a bucket-handle tear on the MRI, and no younger than 15 years, will be invited to participate in the study. Recruitment takes place at the outpatient clinic at the orthopaedic department at Skåne University Hospital in Malmö and the orthopaedic department at Hässleholm hospital.

Ages

15 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 15 years or above. * Displaced longitudinal bucket-handle tear including the posterior horn on MRI and a knee extension deficit. Exclusion Criteria: * Patient younger than 15 years. * Insufficient knowledge of the Swedish language. * Per-operative findings including a bucket-handle rupture in combination with a complete radial rupture

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Region Skåne, Orthopaedic department Kristianstad/Hässleholm

    RECRUITING

    Hässleholm, Skåne County, Sweden

  • Region Skåne, Skåne University Hospital

    RECRUITING

    Malmö, Skåne County, Sweden

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