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Lemon balm supplement tested for stress relief in new study

NCT ID NCT06942897

Symptom relief Sponsor: Azienda di Servizi alla Persona di Pavia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tests whether a daily lemon balm supplement can improve mood and reduce stress in healthy adults. Forty volunteers will take either the supplement or a placebo for 3 weeks. Researchers will measure changes in stress perception and cortisol levels.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Melissa officinalis (lemon balm) extract formulated in phospholipids
What this could lead to
If it works, this could point toward a natural supplement to help manage everyday stress and improve mood.
What could go wrong
This is a very small, early pilot study with only 40 healthy adults over 3 weeks. Results may not apply to people with stress disorders or long-term use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 65 years * Healthy volunteers as assessed by medical history and physical examination * Willingness to comply with the study procedures Exclusion Criteria: * Current use of medications or supplements that may affect mood or cortisol levels * Known allergy or sensitivity to Melissa officinalis or phospholipids * History of psychiatric disorders (e.g., major depression, anxiety disorders) * Significant comorbidities (e.g., cardiovascular, hepatic, renal diseases) * Pregnant or breastfeeding women * Participation in another clinical trial in the past 30 days

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Conditions

The condition(s) this trial relates to.

mood disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Emotional well-being Mood disorders Stress

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.