Which pill stops the flow? mefenamic acid vs tranexamic acid for heavy periods
NCT ID NCT06369012
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested two drugs—mefenamic acid and tranexamic acid—to see which better controls abnormal uterine bleeding in women aged 15 to 45. 130 participants took one of the two medications, and researchers measured how much bleeding decreased. The goal is to find a simple, effective treatment for this common problem.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- mefenamic acid and tranexamic acid
- What this could lead to
- If one drug works better, it could offer a simple, non-surgical option to control heavy menstrual bleeding.
- What could go wrong
- This is a small, completed trial with no phase designation, so results may not apply to all causes of abnormal bleeding. Both drugs have side effects like stomach upset or clotting risks.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
130 people
The number who actually took part.
- Started
-
Mar 2024
- Finished
-
Sep 2024
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
15 to 45 years
- Sex
-
Female participants only
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Any female patient in Child bearing period aging from 15-45 years complaining of Abnormal uterine. * Abnormal uterine bleeding due to endometrial, uterine cavity lesions as diagnosed by TVS or bleeding tendency e.g. Thrombocytopenia, Platelets dysfunction and coagulation defects Exclusion Criteria: * Personal history of renal or hepatic impairment; previous thromboembolic disease, peptic ulcer. * Females with evident drugs intake that cause AUB e.g warfarin, low molecular weight heparin. * Vaginal, vulvar, and cervical causes of bleeding. * Bleeding on top of Use of hormonal and non-hormonal contraception.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ain Shams University Hospitals
Cairo, Egypt
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