New drug combo shows promise in curbing meth addiction
NCT ID NCT06233799
First seen Feb 16, 2026 · Last updated May 21, 2026 · Updated 17 times
Summary
This study tests whether a combination of two medications, extended-release naltrexone and bupropion, can help people with moderate to severe methamphetamine use disorder reduce their drug use. About 360 adults who want to cut back or quit will receive either the medication or a placebo. The main goal is to see if more participants in the medication group have drug-free urine tests after 12 weeks.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CODA
ACTIVE_NOT_RECRUITINGPortland, Oregon, 97214, United States
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Indiana University
RECRUITINGIndianapolis, Indiana, 46202, United States
Contact
Contact
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MUSC/BHS
ACTIVE_NOT_RECRUITINGPickens, South Carolina, 29671, United States
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University of Arkansas for Medical Sciences
RECRUITINGLittle Rock, Arkansas, 72205, United States
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University of California Los Angeles
RECRUITINGLos Angeles, California, 90038, United States
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University of California at San Diego
RECRUITINGSan Diego, California, 92037, United States
Contact Email: •••••@•••••
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University of Kansas Medical Center
RECRUITINGKansas City, Kansas, 66160, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Minnesota
RECRUITINGMinneapolis, Minnesota, 55415, United States
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University of Tennessee
RECRUITINGMemphis, Tennessee, 38119, United States
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University of Texas Southwestern Medical Center
RECRUITINGDallas, Texas, 75247, United States
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University of Virginia
RECRUITINGCharlottesville, Virginia, 22903, United States
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