Text reminders and calls help veterans take lifesaving pills
NCT ID NCT02694185
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a program to help veterans with heart disease or rheumatic conditions take their medications as prescribed. Over 5,000 participants received reminders via text or phone calls, with extra support if needed. The goal was to improve medication adherence and reduce the risk of heart attacks or other serious events.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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5,269 people
The number who actually took part.
- Started
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Oct 2016
- Finished
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Feb 2025
- Lead sponsor
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A government agency
The lead sponsor is a US federal agency other than the NIH.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 95 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Patients will qualify for inclusion if they: 1. Undergo PCI or are prescribed a DMARD. 2. Are prescribed any of the following medications: \[for the IHD intervention\] * Statin * Beta-blocker * Thienopyridines (dual platelet inhibitors) \[for the DMARD intervention\] * Oral methotrexate * Sulfasalazine * Azathioprine * Leflunomide * Tofacitinib * Hydroxychloroquine \[Note: as a study focused on adherence, the investigators will NOT address the appropriateness of prescribed medications, which is an important, but separate issue\] 3. Receive their care from the VA. This is defined by the presence of a VA-assigned-PCP in the year prior to PCI or in the year following PCI (IHD intervention) or in the year prior to or following index DMARD prescription (rheumatic disease intervention). Exclusion Criteria: Patients will be excluded under the following circumstances: * Undergoing only diagnostic (non-interventional) catheterization * Receive their index medicines (listed in item above) from a non-VA source * Discharge to nursing home or skilled nursing facility * Individuals with impaired decision making capacity * Prisoners * Pregnant women * The terminally ill
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD
Baltimore, Maryland, 21201, United States
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Durham VA Medical Center, Durham, NC
Durham, North Carolina, 27705, United States
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Rocky Mountain Regional VA Medical Center, Aurora, CO
Aurora, Colorado, 80045-7211, United States
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San Francisco VA Medical Center, San Francisco, CA
San Francisco, California, 94121, United States
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VA Caribbean Healthcare System, San Juan, PR
San Juan, 00921, Puerto Rico
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