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Study probes whether processed meat or diet pattern matters more for heart risk

NCT ID NCT05589389

Knowledge-focused Sponsor: USDA Beltsville Human Nutrition Research Center Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how different types of meat (minimally processed vs. further processed) combined with different diet patterns affect blood markers related to heart disease risk. Sixty healthy adults followed one of four diet plans for a set period. Researchers measured substances like carnitine, choline, cholesterol, and blood pressure to see how each diet affected heart health. The goal was to better understand which factors matter most for reducing disease risk.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Dietary patterns with minimally or further processed meat
What this could lead to
If results show clear links, this could help people make informed choices about meat and diet for better heart health.
What could go wrong
This is a small, completed observational diet study, not a treatment trial. Findings may not apply to everyone and do not prove cause and effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Oct 2022

Finished

Apr 2026

Lead sponsor

A government agency

The lead sponsor is a US federal agency other than the NIH.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female Exclusion Criteria: * Younger than 25 years old and older than 80 years old at the beginning of the intervention. * Body mass index less than 18 or greater than 40 kg/m2. * Blood pressure greater than 160/100 mm Hg or use of medication to treat hypertension for less than 6 months. * Use of medications that will affect the study outcomes, including cholesterol lowering medications. * Pregnant women, lactating women, women who plan to become pregnant during the study, or women who have given birth during the previous 12 months. * Fasting blood glucose over 125 mg/dL or type 2 diabetes requiring medication. * Body weight change of 10% in the past 3 months. * History of bariatric or other gastrointestinal surgery that would affect digestion. * History or presence of diabetes, kidney disease, liver disease, certain cancers, gout, hyperthyroidism, untreated or unstable hypothyroidism, gastrointestinal disease, pancreatic disease, other metabolic diseases, or malabsorption syndromes. * Smokers, vapers, or other tobacco users (within 6 months prior to the start of the study). * Use of an antibiotic within 1 month of the start of the study or during the study. * Plans to have a colonoscopy during the study. * Allergy to any food included in the study menus. * Unable or unwilling to give informed consent or communicate with study staff. * Self-report of alcohol or substance abuse within the past 12 months and/or current acute treatment or rehabilitation program for these problems (long-term participation in Alcoholics Anonymous is not an exclusion). * Other medical, psychiatric, or behavioral factors that in the judgment of the Principal Investigator may interfere with study participation or the ability to follow the intervention protocol.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy volunteers

Contacts and locations

Locations

  • USDA-ARS, Beltsville Human Nutrition Research Center

    Beltsville, Maryland, 20705, United States

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