Can when you eat protect your brain from MS?
NCT ID NCT07475377
First seen Jun 27, 2026 · Last updated Jul 14, 2026 · Updated 2 times
Summary
This study looks at whether the time of day you eat can affect brain health in people with multiple sclerosis. Twenty-two adults with MS will follow a daily eating schedule for a set period. Researchers will measure markers of nerve health and inflammation in the blood. A small group will also get brain scans to see if meal timing affects inflammation in the brain.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 22 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 64 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosed with relapsing remitting or secondary progressive multiple sclerosis (RRMS or SPMS) * If on disease modifying therapy (DMTs), stable for 6 months * If not on DMTs, no DMT usage within previous 6 months * BMI 18.5-50 kg/m2 * Access to a smartphone * Responsible for personal eating schedule or able to have input into schedule Exclusion Criteria: * Relapse within previous 30 days * Actively engaged in a weight loss program or unwilling to follow assigned eating schedule * Current use of GLP-1 or use within previous 3 months * Regularly fasts \> 12 hours/day * Employed in night shift or rotating shift work * Unable to walk 25 feet with or without assistive device (EDSS \> 6.5). * Current use of insulin or sulfonylurea agents * Pregnant or breastfeeding * Currently enrolled in another trial that would confound results (e.g., exercise studies or other diet studies)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Alabama at Birmingham
Birmingham, Alabama, 35294, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a common antihistamine boost multiple sclerosis treatment?
- Can exercise rebuild muscle and balance in MS?
- Can diet ease the crushing fatigue of multiple sclerosis?
- One-Time CAR-T infusion tested against progressive MS
- Can PET scans reveal hidden brain inflammation in MS?