Dietary formula shows promise for psoriatic arthritis symptom relief
NCT ID NCT06990152
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a food formula containing medium-chain triglycerides (MCTs) and vegetable fibers could improve quality of life in 72 adults with psoriatic arthritis and low disease activity. Participants took the formula for 3 months while continuing their usual medications. The main goal was to see if it helped with daily living, pain, and mood. This is a completed early-stage study, so results are not yet confirmed.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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72 people
The number who actually took part.
- Started
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May 2025
- Finished
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Feb 2026
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients: aged 18-80 years; * Clinical diagnosis of PsA meeting the CASPAR classification criteria; * Low disease activity (4 \< DAPSA ≤ 14) at the time of recruitment; * Under stable pharmacological treatment with disease-modifying antirheumatic drugs (DMARDs) (conventional synthetic, targeted synthetic, or biological); * Disease duration \> 6 months; * Absence of metabolic diseases. Exclusion Criteria: * BMI ≥ 27 kg/m²; * Current or desired pregnancies (confirmed by pregnancy test); * Disease activity in remission (DAPSA ≤ 4), moderate (14 \< DAPSA ≤ 28), or high (DAPSA \> 28) at the time of recruitment; * Pediatric onset of the disease (\< 16 years); * Patients on a vegan, ketogenic, or MCT-rich diet (containing MCT in supplement form or high amounts of palm or coconut oil); * Presence of ketoacidosis/metabolic acidosis, decompensated liver cirrhosis, or medium-chain acyl-CoA dehydrogenase (MCAD) deficiency; * Type 2 diabetes, cardiovascular diseases, hypertension, ischemic diseases, renal failure, malignant tumors, respiratory diseases, dyslipidemia, fibromyalgia, metabolic syndrome; * Major depression; * Gastritis, esophagitis, reflux syndrome, chronic inflammatory bowel diseases (IBD); * Lactose intolerance.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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ASST Gaetano Pini CTO, UOC Clinica Reumatologica
Milan, Italy, 20122, Italy
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Other studies related to the condition(s) this trial covers.
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