100,000 volunteers help scientists predict disease before symptoms appear
NCT ID NCT07332598
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This observational study at Mayo Clinic aims to understand how genetics and environment contribute to disease before it begins. Researchers will collect biological samples, voice recordings, and survey data from 100,000 adult Mayo Clinic patients. The goal is to build a comprehensive dataset to predict and ultimately prevent serious illness.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help identify early warning signs and potential targets to stop diseases before they start.
- What could go wrong
- This is an observational study, not a treatment trial. It may not lead directly to any new therapies or cures.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Dec 2035
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Mayo Clinic patients
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years * Registered Mayo Clinic patient * Able to provide informed written consent * Able to receive mail and packages within a United States (US) state * Able to collect and ship samples within a US state via FedEx for overnight delivery Exclusion Criteria: * Active hematological cancer or history of a hematological cancer * Allogeneic Bone Marrow Transplant (autologous bone marrow transplant recipients are acceptable if collected at least one month after transplant) * Other co-morbidity that, in physician's opinion, would interfere with patient's ability to participate in the study (e.g., reduced ability to comprehend, i.e., dementia, intellectual disability, etc.)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
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