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Could a gentle vibration treatment ease carpal tunnel pain?

NCT ID NCT07660913

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 09, 2026 · Updated 2 times

Summary

This study investigates whether matrix rhythm therapy, a device that delivers gentle vibrations to the hand and arm, can reduce symptom severity and improve hand function in people with mild-to-moderate carpal tunnel syndrome. Participants receive either active or sham therapy twice a week for six weeks, alongside standard care. The trial measures changes in symptoms, grip strength, and quality of life over 12 weeks.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Matrix rhythm therapy (device-based vibration treatment)
What this could lead to
If effective, this therapy could offer a non-surgical, drug-free option to ease pain and numbness and improve hand function in carpal tunnel syndrome.
What could go wrong
This is a small, early-stage trial with 84 participants. The sham device mimics vibration, so any benefit may be due to a placebo effect. Results may not apply to severe cases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 84 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Having a diagnosis of unilateral carpal tunnel syndrome confirmed by an orthopedist based on clinical examination and electromyography (EMG) testing. * Being classified with mild-to-moderate carpal tunnel syndrome severity. * Having symptoms persisting for at least 12 weeks. * Having a Mini-Mental State Examination (MMSE) score greater than 24. * Being literate (able to read and write). Exclusion Criteria: * History of prior carpal tunnel release surgery. * History of corticosteroid injection into the affected hand/wrist. * Having received physiotherapy for carpal tunnel syndrome within the last 6 months. * Presence of any neurological signs or symptoms in the upper extremity other than carpal tunnel syndrome. * History of prior surgery in the hand or wrist region due to other conditions. * Diagnosis of any systemic neurological disease. * Diagnosis of rheumatic diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus). * Having ongoing pain in the arm or hand due to any other underlying cause.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Izmir Bakircay University

    RECRUITING

    Izmir, 35665, Turkey (Türkiye)

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