Could a gentle vibration treatment ease carpal tunnel pain?
NCT ID NCT07660913
First seen Jun 27, 2026 · Last updated Jul 09, 2026 · Updated 2 times
Summary
This study investigates whether matrix rhythm therapy, a device that delivers gentle vibrations to the hand and arm, can reduce symptom severity and improve hand function in people with mild-to-moderate carpal tunnel syndrome. Participants receive either active or sham therapy twice a week for six weeks, alongside standard care. The trial measures changes in symptoms, grip strength, and quality of life over 12 weeks.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Matrix rhythm therapy (device-based vibration treatment)
- What this could lead to
- If effective, this therapy could offer a non-surgical, drug-free option to ease pain and numbness and improve hand function in carpal tunnel syndrome.
- What could go wrong
- This is a small, early-stage trial with 84 participants. The sham device mimics vibration, so any benefit may be due to a placebo effect. Results may not apply to severe cases.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 84 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2026
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Having a diagnosis of unilateral carpal tunnel syndrome confirmed by an orthopedist based on clinical examination and electromyography (EMG) testing. * Being classified with mild-to-moderate carpal tunnel syndrome severity. * Having symptoms persisting for at least 12 weeks. * Having a Mini-Mental State Examination (MMSE) score greater than 24. * Being literate (able to read and write). Exclusion Criteria: * History of prior carpal tunnel release surgery. * History of corticosteroid injection into the affected hand/wrist. * Having received physiotherapy for carpal tunnel syndrome within the last 6 months. * Presence of any neurological signs or symptoms in the upper extremity other than carpal tunnel syndrome. * History of prior surgery in the hand or wrist region due to other conditions. * Diagnosis of any systemic neurological disease. * Diagnosis of rheumatic diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus). * Having ongoing pain in the arm or hand due to any other underlying cause.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Izmir Bakircay University
RECRUITINGIzmir, 35665, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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