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Hands-On therapy eases jaw pain for rheumatoid arthritis patients

NCT ID NCT07171671

Symptom relief Sponsor: Sanko University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested two types of manual therapy (myofascial mobilization and joint mobilization) in 57 people with rheumatoid arthritis who also had jaw joint problems. Participants received therapy twice a week for six weeks, while a control group got no treatment. Both therapy groups showed improvements in jaw movement, pain, headache, and anxiety compared to the control group. The results suggest manual therapy may help manage jaw symptoms in rheumatoid arthritis, but larger studies are needed to confirm these findings.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
manual therapy (myofascial mobilization and joint mobilization)
What this could lead to
If these manual therapy techniques prove effective in larger studies, they could offer a drug-free way to ease jaw pain and improve jaw function in people with rheumatoid arthritis.
What could go wrong
This was a small, completed study with only 57 participants. The results need to be confirmed in larger, longer-term trials before we can be sure how well these therapies work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

57 people

The number who actually took part.

Started

Oct 2024

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Be aged between 18 and 65 * Have been diagnosed with rheumatoid arthritis according to the ACR/EULAR 2010 criteria * Be in the chronic phase of the disease * Have temporomandibular joint dysfunction according to the RDC/TMD criteria * Have intact cognitive functions * Individuals who agree to participate in the study and sign the informed consent form Exclusion Criteria: * \- Maksillofasiyal travma ve cerrahi öyküsü olanlar * Son 6 ayda ortodontik tedavi öyküsü olanlar * Trigeminal nevralji ve/veya fasiyal sinir paralizisi öyküsü olanlar * Romatoid Artrit dışında ek bir romatolojik hastalığı olanlar * Ağız içi splint kullanıyor olmak * Protez diş kullanımı ve molar dişlerde eksiklik * Servikal bölgeye ve temporomandibular eklem disfonksiyonuna yönelik son 6 ayda Manuel - Terapi, enjeksiyon vb. benzeri tedavi görmüş olmak

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Conditions

The condition(s) this trial relates to.

Pain rheumatic disorder rheumatoid arthritis temporomandibular joint disorder temporomandibular joint dysfunction syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Manuel therapy Rheumatic diseases Temporomandibular joint dysfunction

Contacts and locations

Locations

  • Sanko Unıversıty

    Gaziantep, Gaziantep, 27090, Turkey (Türkiye)

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