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Pregnancy stress linked to Baby's brain? new study digs deeper

NCT ID NCT07432243

Knowledge-focused Sponsor: Institute for Human Development and Potential (IHDP), Singapore Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how a mother's stress, anxiety, and mood during pregnancy might influence her child's brain development and behavior. Researchers are following 587 families in Singapore, including mothers, fathers, and children. They use brain scans and developmental tests to understand these connections, also considering the father's genetics and parenting style.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help identify which aspects of maternal stress most influence child development, leading to better support for pregnant women.
What could go wrong
This is an observational study, not a treatment trial. It cannot prove cause and effect, and results may not apply to all populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

587 people

The number who actually took part.

Started

Sep 2021

Expected to finish

Jun 2031

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Singapore residents

Ages

21 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Mother: 1. Enrolled in MAMS study 2. Intends for herself and her child to stay in Singapore for the next 5 years 3. Access to a smartphone or standard laptop/ desktop 4. Willing to take part in this study and able to provide written consent 5. Aged 21-42 years Father: 1. Partner is already enrolled in MAMS study 2. Aged 21-75 years Exclusion Criteria: Mother: 1. Women with pre-existing or a history of psychotic depression, schizophrenia and bipolar disorders 2. Women currently on oral/IV steroids and/or thyroids medication 3. Women with a history of thyroid disease 4. Women currently involved in on-going interventional randomized controlled trials

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Conditions

The condition(s) this trial relates to.

inherited disease susceptibility Neurologic Manifestations Psychological Well-Being

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Genetic susceptibility Neurological and mental health conditions Psychology, social Socioeconomic factors

Contacts and locations

Locations

  • Institute for Human Development and Potential

    Singapore, 117609, Singapore

More trials for these conditions

Other studies related to the condition(s) this trial covers.