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New bed nets take on mosquito resistance in malaria battle

NCT ID NCT05796193

Disease control Sponsor: London School of Hygiene and Tropical Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial compares two new types of insecticide-treated bed nets against standard nets to see if they better prevent malaria in children aged 6 months to 10 years in central Côte d'Ivoire. About 1,650 people are taking part across multiple villages. The new nets contain either a chemical booster (PBO) or a second insecticide (chlorfenapyr) to overcome mosquito resistance. The study also looks at infection rates in all ages and mosquito numbers over three years.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Insecticide-treated bed nets (Veeralin with alpha-cypermethrin and PBO, Interceptor G2 with alpha-cypermethrin and chlorfenapyr, or standard alpha-cypermethrin-only nets)
What this could lead to
If successful, these next-generation nets could provide better protection against malaria in areas where mosquitoes are resistant to standard insecticides, helping to keep malaria control on track.
What could go wrong
This is a field trial in one region of Côte d'Ivoire, and results may not apply everywhere. Mosquito resistance can change over time, and the nets' effectiveness may decrease with wear and tear.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 1,650 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2023

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

6 months and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * For adults: willing to participate and provide consent * For children: Having a parents/adult caregiver willing to provide written consent for the household and clinical survey and assent for children over 10 * Residing in the village over the last 3 months * Be aged 6 months to 9 years old at time of recruitment (for the cohort) Exclusion Criteria: * Children who are expected to be non-resident over the period of study will be excluded (for the cohort) * Dwelling not found or vacant during the survey (for prevalence and entomological surveys) * No adult caregiver capable to give informed consent (All activities) * Habitants/selected participants severely ill

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Conditions

The condition(s) this trial relates to.

malaria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Malaria

Contacts and locations

Locations

  • Institut Pierre Richet

    Bouaké, Côte d’Ivoire

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Other studies related to the condition(s) this trial covers.