New bed nets take on mosquito resistance in malaria battle

NCT ID NCT05796193

First seen Mar 24, 2026 · Last updated Jun 23, 2026 · Updated 11 times

Summary

This trial compares two new types of insecticide-treated bed nets against standard nets to see if they better prevent malaria in children aged 6 months to 10 years in central Côte d'Ivoire. About 1,650 people are taking part across multiple villages. The new nets contain either a chemical booster (PBO) or a second insecticide (chlorfenapyr) to overcome mosquito resistance. The study also looks at infection rates in all ages and mosquito numbers over three years.

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Contacts and locations

Locations

  • Institut Pierre Richet

    Bouaké, Côte d’Ivoire

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Insecticide-treated bed nets (Veeralin with alpha-cypermethrin and PBO, Interceptor G2 with alpha-cypermethrin and chlorfenapyr, or standard alpha-cypermethrin-only nets)

What this could lead to

If successful, these next-generation nets could provide better protection against malaria in areas where mosquitoes are resistant to standard insecticides, helping to keep malaria control on track.

What could go wrong

This is a field trial in one region of Côte d'Ivoire, and results may not apply everywhere. Mosquito resistance can change over time, and the nets' effectiveness may decrease with wear and tear.

Conditions

The condition(s) this trial relates to.

malaria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.