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Could a machine beat the human hand for Pain-Free injections?

NCT ID NCT07533526

First seen Apr 21, 2026 · Last updated Jun 23, 2026 · Updated 8 times

Summary

This study compares two ways of giving a large-volume subcutaneous injection of pertuzumab and trastuzumab (Phesgo) to breast cancer patients: one using a machine that injects at a constant speed, and the other using a nurse's hand. Forty female patients will receive both methods in different treatment cycles to see which causes less pain. The goal is to find a more comfortable injection technique.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Medical Ethics Committee of Sun Yat-sen Memorial Hospital, Sun Yat-sen University

    Guangzhou, Guangdong, 510000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

pertuzumab and trastuzumab (Phesgo)

What this could lead to

If it works, this could lead to a less painful way to give large-volume subcutaneous injections, improving the treatment experience for breast cancer patients.

What could go wrong

This is a small, early-stage study with only 40 patients, so results may not apply to everyone. The manual injection is timed to match the machine, so differences in pain may be small.

Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm HER2 positive breast carcinoma Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.