Could a simple machine take the sting out of breast cancer injections?
NCT ID NCT07533526
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two ways of giving a large-volume subcutaneous injection of targeted therapy (pertuzumab and trastuzumab) to 40 women with HER2-positive breast cancer. Each patient will receive one injection by a nurse using a stopwatch to mimic a steady speed, and another injection by a medical pump that delivers the drug at a constant rate. The goal is to see which method causes less pain, with the hope that machine-driven injections could improve the treatment experience.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- pertuzumab and trastuzumab (Phesgo) given via subcutaneous injection
- What this could lead to
- If successful, this could show that using a machine for slow, steady injections reduces pain and improves comfort for breast cancer patients.
- What could go wrong
- This is a small, early-stage study with only 40 patients, so results may not apply to everyone. The manual injection is timed to match the machine, so any difference in pain might be small.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Medical Ethics Committee of Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Guangzhou, Guangdong, 510000, China
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