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AI model aims to predict spine curve worsening in teens with scoliosis

NCT ID NCT07556042

Knowledge-focused Sponsor: Istanbul University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 20, 2026 · Updated 2 times

Summary

This study is developing a machine learning model to predict whether the spine curve in teens with adolescent idiopathic scoliosis will worsen after a 12-week core stabilization exercise program. Researchers will collect data from 30 participants aged 10-18 with mild to moderate curves. The goal is to create a tool that helps doctors decide who needs bracing or surgery and who can be safely monitored, potentially reducing overtreatment and unnecessary X-rays.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Core stabilization exercise program
What this could lead to
If successful, this could lead to a tool that helps doctors predict which teens with scoliosis will worsen, reducing unnecessary bracing, surgery, and X-ray exposure.
What could go wrong
This is a small, early study with only 30 participants, so the model may not be accurate for all patients. The results are not a treatment and need further validation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2026

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

10 to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * being between the ages of 10 and 18 * having a Cobb angle between 10 and 40 degrees * not receiving any other exercise treatment (scoliosis-specific exercises, etc.) from a different center that would affect the patient's scoliosis Exclusion Criteria: * history of scoliosis surgery * patients who had undergone any type of surgical procedure within the last 3 months were excluded * orthopedic, neurological, or systemic diseases that would hinder exercise * Intellectual, behavioral, or communication disorders affecting understanding of instructions or exercise performance, or participation in any exercise

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Conditions

The condition(s) this trial relates to.

adolescent idiopathic scoliosis scoliosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Adolescence idiopathic scoliosis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Bezmialem Vakif University

    RECRUITING

    Istanbul, Turkey (Türkiye)

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