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Can a targeted nerve block cut opioid use after hysterectomy?

NCT ID NCT07740252

Symptom relief Sponsor: Namik Kemal University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 31, 2026 · Last updated Jul 31, 2026

Summary

This study looks at whether a modified nerve block, called M-TAPA, can reduce pain and the need for painkillers after a laparoscopic hysterectomy. Researchers will compare patients who received this block with those who had standard anesthesia and pain management. The main focus is on how much tramadol, a strong painkiller, is used in the first 24 hours after surgery. The study also checks pain scores, recovery quality, and any side effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Modified thoracoabdominal nerve block through a perichondrial approach (M-TAPA) using bupivacaine
What this could lead to
If effective, this nerve block could become a standard part of pain management for hysterectomy, reducing the need for opioids and improving recovery.
What could go wrong
This is a small retrospective study, so results may be influenced by bias or confounding. The block may not consistently reduce pain or opioid use, and there are risks like nerve damage or local anesthetic toxicity.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

60 people

The number who actually took part.

Started

Dec 2023

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Female patients aged 18-65 years with ASA physical status I-II who underwent elective total laparoscopic hysterectomy at Tekirdag Namik Kemal University Faculty of Medicine Hospital between December 25, 2023, and December 25, 2024.

Ages

18 to 65 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female patients aged 18 to 65 years. * American Society of Anesthesiologists (ASA) physical status I or II. * Undergoing elective total laparoscopic hysterectomy under general anesthesia. * Availability of complete perioperative and postoperative medical records. Exclusion Criteria: * Neurological disorders affecting pain perception. * Coagulopathy or bleeding disorders. * Known allergy to local anesthetics. * Chronic opioid use before surgery. * Body mass index (BMI) greater than 35 kg/m². * Incomplete medical records.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hysterectomy Postoperative pain

Contacts and locations

Locations

  • Tekirdag Namik Kemal University Faculty of Medicine Hospital

    Tekirdağ, Tekirdağ, 59030, Turkey (Türkiye)

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