Can a targeted nerve block cut opioid use after hysterectomy?

NCT ID NCT07740252

First seen Jul 31, 2026 · Last updated Jul 31, 2026

Summary

This study looks at whether a modified nerve block, called M-TAPA, can reduce pain and the need for painkillers after a laparoscopic hysterectomy. Researchers will compare patients who received this block with those who had standard anesthesia and pain management. The main focus is on how much tramadol, a strong painkiller, is used in the first 24 hours after surgery. The study also checks pain scores, recovery quality, and any side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Modified thoracoabdominal nerve block through a perichondrial approach (M-TAPA) using bupivacaine
What this could lead to
If effective, this nerve block could become a standard part of pain management for hysterectomy, reducing the need for opioids and improving recovery.
What could go wrong
This is a small retrospective study, so results may be influenced by bias or confounding. The block may not consistently reduce pain or opioid use, and there are risks like nerve damage or local anesthetic toxicity.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Tekirdag Namik Kemal University Faculty of Medicine Hospital

    Tekirdağ, Tekirdağ, 59030, Turkey (Türkiye)

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