New study monitors safety of LYNPARZA in pancreatic cancer patients with BRCA mutation

NCT ID NCT04889404

Completed Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jan 17, 2026 · Last updated May 23, 2026 · Updated 16 times

Summary

This study looked at the safety of the drug LYNPARZA when used as a long-term treatment after chemotherapy in 130 people with a type of pancreatic cancer linked to BRCA gene changes. The goal was to track side effects like bone marrow problems, lung issues, new cancers, and risks to unborn babies. The study did not test if the drug works better than other options, but gathered real-world safety data.

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Contacts and locations

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Locations

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Osaka, Lyn010001, D081FC00004, Japan
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Kanagawa, Lyn010003, D081FC00004, Japan
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Okayama, Lyn010004, D081FC00004, Japan
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Akita, Lyn010005, D081FC00004, Japan
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Niigata, Lyn010006, D081FC00004, Japan
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Shizuoka, Lyn010007, D081FC00004, Japan
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Niigata, Lyn010008, D081FC00004, Japan
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Tokyo, Lyn010009, D081FC00004, Japan
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Saitama, Lyn010010, D081FC00004, Japan
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Aichi, Lyn010011, D081FC00004, Japan
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Osaka, Lyn010012, D081FC00004, Japan
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Tokyo, Lyn010013, D081FC00004, Japan
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Nara, Lyn010014, D081FC00004, Japan
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Wakayama, Lyn010015, D081FC00004, Japan
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Miyagi, Lyn010016, D081FC00004, Japan
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Tokyo, Lyn010017, D081FC00004, Japan
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Osaka, Lyn010018, D081FC00004, Japan
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Gunma, Lyn010019, D081FC00004, Japan
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Hiroshima, Lyn010020, Japan
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Tochigi, Lyn010021, D081FC00004, Japan
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Numakunai, Lyn010022, D081FC00004, Japan
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Osaka, Lyn010025, D081FC00004, Japan
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Shizuoka, Lyn010026, D081FC00004, Japan
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Nagasaki, Lyn010027, D081FC00004, Japan
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Kumamoto, Lyn010028, D081FC00004, Japan
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Saitama, Lyn010029, D081FC00004, Japan
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Nagano, Lyn010031, D081FC00004, Japan
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Hyōgo, Lyn010032, D081FC00004, Japan
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Shimane, Lyn010033, D081FC00004, Japan
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Hyōgo, Lyn010034, D081FC00004, Japan
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Shizuoka, Lyn010035, D081FC00004, Japan
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Hyōgo, Lyn010036, D081FC00004, Japan
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Okayama, Lyn010038, D081FC00004, Japan
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Fukuoka, Lyn010041, Japan
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Hokkaido, Lyn010042, Japan
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Ehime, Lyn010044, Japan
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Osaka, Lyn010045, Japan
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Shizuoka, Lyn010047, Japan
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Tokyo, Lyn010050, Japan
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Aichi, Japan
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Chiba, Japan
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Fukuoka, Japan
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Gunma, Japan
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Hiroshima, Japan
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Hokkaido, Japan
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Hyōgo, Japan
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Ibaraki, Japan
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Kagawa, Japan
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Kanagawa, Japan
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Kyoto, Japan
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Nagano, Japan
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Nagasaki, Japan
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Nara, Japan
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Okayama, Japan
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Osaka, Japan
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Shizuoka, Japan
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Tokyo, Japan
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Tottori, Japan
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Toyama, Japan
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Yamagata, Japan

Conditions

Explore the condition pages connected to this study.

PANCREATIC NEOPLASMS