New study tests better way to treat Post-Mastectomy arm swelling
NCT ID NCT07217288
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two treatments for arm swelling (lymphedema) that can happen after breast cancer surgery. The goal is to see which therapy works better to reduce pain, swelling, and improve movement and quality of life. The study will include 52 women aged 30-60 who had a mastectomy at least three months ago and have completed chemotherapy or radiation.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 52 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2025
An estimate. Start dates often move.
- Expected to finish
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Apr 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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30 to 60 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Females with age between 30 to 60 years. (Monticciolo et al., 2021) * Females with unilateral mastectomy post three months of surgery. (Shen et al., 2023) 21 * A volume difference to the circumferential measurements between the affected and unaffected upper extremities of more volume difference\>10%. * Completed chemotherapy and/or radiation therapy. (Borman, Yaman, Yasrebi, İnanlı, \& Dönmez, 2022) Exclusion Criteria: * Systemic disorders that might contraindicate the use of sequential compression therapy i.e. chronic kidney disease with renal failure, Congestive heart failure, neurological disorders, respiratory disorders. * Presence of active cellulitis, open and partially healed wounds. * Patients with lipedema * Active or recurrent cancer (defined as \< 3 months since completion of cancer therapy) * An acute infection within the previous 4 weeks * Active venous thromboembolic edema * Pregnant women and women who are planning or nursing at study entry. * Patients who had participated in any clinical trial of an investigational substance or device during the previous 30 days * Potential patients with a cognitive or physical impairment that would interfere with appropriate use of the device. (Rockson, Whitworth, et al., 2022)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Cancer Care Hospital
Lahore, Punjab Province, 74600, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Simple exercises may improve balance for breast cancer survivors with lymphedema
- New combo therapy eases Post-Mastectomy pain and swelling
- New wearable device eases arm swelling in breast cancer survivors
- Gentle touch therapy tested for breast cancer arm swelling
- Can microsurgery beat standard therapy for Post-Cancer lymphedema?
- New procedure may stop debilitating arm swelling after breast cancer surgery