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Ticks recruited to sniff out hidden lyme bacteria in patients

NCT ID NCT01143558

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 26 times

Summary

This study tested a special method called xenodiagnosis to see if Lyme disease bacteria can survive after antibiotic treatment. Researchers placed disease-free ticks on the skin of 45 adults with different stages of Lyme disease, as well as healthy volunteers. The goal was to see if the ticks could pick up any remaining bacteria that standard tests might miss, helping explain why some people have lasting symptoms.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

  • Tufts University

    Boston, Massachusetts, 01536, United States

  • Yale University

    New Haven, Connecticut, 06510-8005, United States

Conditions

Explore the condition pages connected to this study.