New drug combo aims to stop lung transplant failure
NCT ID NCT06033196
First seen Oct 31, 2025 · Last updated May 24, 2026 · Updated 31 times
Summary
This study tests whether adding tocilizumab to standard anti-rejection drugs can prevent chronic lung allograft dysfunction (CLAD), the main cause of lung transplant failure. 350 lung transplant recipients will receive either tocilizumab or a placebo over 20 weeks, alongside their usual medications. The goal is to see if this approach reduces the risk of CLAD, needing another transplant, or death.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Barnes Jewish Hospital/ Washington University SOM (Site #: 71191)
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Boston Children's Hospital and Harvard Medical School (Site #: 71001)
WITHDRAWNBoston, Massachusetts, 02215, United States
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Cedars Sinai Medical Center (Site #: 71146)
RECRUITINGBeverly Hills, California, 90211, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cleveland Clinic (Site #: 71101)
RECRUITINGCleveland, Ohio, 44195, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Columbia University Medical Center (Site #: 71113)
RECRUITINGNew York, New York, 10032, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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David Geffen School of Medicine at UCLA (Site #: 71123)
RECRUITINGLos Angeles, California, 90095, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Duke University Medical Center (Site #: 71139)
RECRUITINGDurham, North Carolina, 27710, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Emory University (Site #: 71103)
NOT_YET_RECRUITINGAtlanta, Georgia, 55905, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Houston Methodist Hospital (Site #: 71120)
WITHDRAWNHouston, Texas, 77030, United States
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Massachusetts General Hospital (Site #: 71107)
RECRUITINGBoston, Massachusetts, 02114, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mayo Clinic Rochester (Site #: 71160)
NOT_YET_RECRUITINGRochester, Minnesota, 55905, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ohio State University Medical Center (Site #: 71196)
NOT_YET_RECRUITINGColumbus, Ohio, 43210, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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St. Joseph's Hospital and Medical Center (Site #: 71192)
RECRUITINGPhoenix, Arizona, 85013, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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St. Louis Children's Hospital of Washington University (Site #: 71006)
WITHDRAWNSt Louis, Missouri, 63110, United States
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Temple University (Site #: 71197)
NOT_YET_RECRUITINGPhiladelphia, Pennsylvania, 19140, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Florida Shands Hospital (Site #: 71131)
NOT_YET_RECRUITINGGainesville, Florida, 32610, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Maryland Medical Center (Site #: 71138)
WITHDRAWNBaltimore, Maryland, 21201, United States
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University of Texas Health Science at San Antonio (Site #: 71198)
NOT_YET_RECRUITINGSan Antonio, Texas, 78229, United States
Contact Email: •••••@•••••
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University of Texas Southwestern (Site #: 71187)
RECRUITINGDallas, Texas, 75390, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Utah Medical Center (Site #: 71126)
RECRUITINGSalt Lake City, Utah, 84132, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vanderbilt University (Site #: 71174)
NOT_YET_RECRUITINGNashville, Tennessee, 37232-0393, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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