LUNG TRANSPLANT

This study tests whether the drug belumosudil can prevent chronic lung allograft dysfunction (CLAD) in people who have had a lung transplant and show signs of early rejection or inflammation. About 234 participants will receive either belumosudil or a placebo for 52 weeks, alongs…

This study tests whether adding tocilizumab to standard anti-rejection drugs can prevent chronic lung allograft dysfunction (CLAD), the main cause of lung transplant failure. 350 lung transplant recipients will receive either tocilizumab or a placebo over 20 weeks, alongside thei…

This early study tests a new way to use a heart-lung machine (ECMO) to keep people with severe lung disease and heart failure alive until they can get a lung transplant. The approach uses a special tube placed across the heart's wall to improve blood flow. Only 4 participants wil…

This study looks at whether one-on-one health coaching over the phone can help people waiting for a lung transplant feel more in control and emotionally stronger. About 230 adults on the transplant list will either get up to 12 coaching sessions or standard care. Researchers will…

This study looks at whether 12 sessions of Latin dance can improve wellbeing in people who have had a lung transplant. Researchers will measure changes in anxiety, depression, balance, and fear of movement. The study involves 52 participants who are able to walk and have complete…

This study aims to understand why some people who get a lung transplant develop rejection while others do not. Researchers will follow 100 adults aged 18 to 75 who have had or are waiting for a lung transplant. Participants will have regular check-ups, blood tests, lung function …

This registry will collect data from up to 10,000 lung transplant recipients across the US. The goal is to see how well donor lungs preserved with the OCS Lung system perform in the real world after FDA approval. Researchers will track patient and graft survival for one year and …

This study collects tissue samples from 7,000 adults with lung cancer, COPD, lung transplants, or other chest diseases. The samples are stored in a repository to help researchers better understand how these diseases start, how to diagnose them early, and how to improve treatment.…