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Special MRI could spot lung rejection early, saving transplants

NCT ID NCT07046910

First seen Mar 27, 2026 · Last updated Jun 22, 2026 · Updated 15 times

Summary

This study tests whether a special MRI using inhaled xenon gas can detect early signs of rejection in lung transplant patients. Researchers will compare MRI results with lung function tests and cell analysis from fluid samples. The goal is to find a non-invasive way to catch rejection sooner, which could help prevent long-term graft failure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Virginia

    RECRUITING

    Charlottesville, Virginia, 22908, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Hyperpolarized Xenon-129 gas

What this could lead to

If successful, this MRI method could allow doctors to detect lung transplant rejection earlier and more accurately, potentially improving patient outcomes.

What could go wrong

This is a small, early-phase study (60 participants) focused on diagnosis, not treatment. The MRI technique may not prove reliable enough for routine use.

Conditions

The condition(s) this trial relates to.

transplant rejection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.