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Could a simple breathing trick during surgery save your lungs?

NCT ID NCT07325812

Knowledge-focused Sponsor: Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether doing periodic lung recruitment maneuvers (a technique to reopen collapsed lung areas) during spine surgery helps reduce lung collapse compared to the standard single-time approach. Sixty adults having elective spine surgery while lying face-down will be randomly assigned to either periodic or standard maneuvers. Lung health will be checked using ultrasound, a non-invasive imaging method.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Alveolar Recruitment Maneuver (a breathing technique to reopen collapsed lung areas during surgery)
What this could lead to
If it works, this could point toward a better way to protect patients' lungs during spine surgery, reducing complications.
What could go wrong
This is a small, early-stage study with only 60 participants, so results may not apply to all patients. The technique is already used routinely, so any benefit may be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Apr 2026

An estimate. Start dates often move.

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 to 65 years * Scheduled for elective lumbar spine surgery under general anesthesia * Surgery planned to be performed in the prone position * Expected surgical duration of at least 2 hours * American Society of Anesthesiologists (ASA) physical status I-II * Ability to provide written informed consent Exclusion Criteria: * Body mass index (BMI) greater than 30 kg/m² * History of thoracic surgery * Known or suspected chronic pulmonary disease (e.g., chronic obstructive pulmonary disease, restrictive lung disease) * Clinically significant cardiac disease * Pregnancy or breastfeeding * Known airway anomalies Intraoperative surgical duration shorter than 2 hours Refusal or inability to provide informed consent

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Conditions

The condition(s) this trial relates to.

middle lobe syndrome Pulmonary Atelectasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atelectasis General anesthesia Mechanical ventilation Prone position

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization

    RECRUITING

    Istanbul, Turkey (Türkiye)

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