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Yearly CT scans aim to catch lung cancer early in mexican smokers and Wood-Smoke exposed

NCT ID NCT06535451

Diagnosis Sponsor: Instituto Nacional de Cancerologia de Mexico Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will give yearly low-dose CT scans to 1,000 people in Mexico who are at high risk for lung cancer—including heavy smokers, former smokers, and those exposed to wood smoke. The goal is to see if regular screening can find lung cancer at an earlier, more treatable stage. Participants will also have lung function tests and blood tests over three years, with follow-up lasting up to 10 years.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
low-dose computed tomography (LDCT) scan
What this could lead to
If successful, this could show that annual LDCT screening helps catch lung cancer earlier in high-risk populations, potentially improving survival rates.
What could go wrong
This is an observational screening study, not a treatment trial. It may not prove that screening reduces deaths, and false positives could cause unnecessary anxiety or procedures.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 1,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2022

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Mexican population aged over 50 years with lung cancer risk factors

Ages

50 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Eligible participants over fifty years old and one of the next criteria: * Current smokers (\>20 pack-years) * Former smokers (\>20 pack-years) who have quit within the past 15 years, * Non-smokers exposed to wood smoke more than 100 hours/year * Patients diagnosed with Chronic Obstructive Pulmonary Disease (COPD). Exclusion Criteria: * Subjects who cannot be examined by tomography due to physical limitations such as weight. * History of any type of cancer within the last five years, except non-melanoma skin cancer. * Symptoms consistent with some malignant neoplasm. * People with a poor physical-emotional condition that reduces their life expectancy or does not ensure adherence to the study. Elimination Criteria • Withdrawal of informed consent

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lung cancer

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Instituto Nacional de Cancerologia (INCan) Mexico

    RECRUITING

    Mexico City, Tlalpan, 14080, Mexico

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