Online program aims to slash dementia risk with personalized lifestyle coaching
NCT ID NCT06748625
First seen Jun 27, 2026 · Last updated Aug 26, 2026 · Updated 2 times
Summary
This study tests an online program called Luci that helps people aged 50 to 75 adopt healthier habits to lower their risk of dementia. The program provides educational materials, tips, and a personal coach to guide participants in improving physical activity, diet, and mental engagement. Researchers want to see if the program leads to meaningful lifestyle changes over 24 weeks.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Luci Coach-Assisted Intervention (behavioral program via web platform with coach support)
- What this could lead to
- If successful, this program could become an effective tool to help people reduce their risk of dementia through lifestyle changes.
- What could go wrong
- This is a behavioral intervention, so results depend on participants sticking with the program. The study measures lifestyle changes, not dementia itself, so it's unclear if these changes actually prevent cognitive decline.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
-
About 370 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Mar 2025
- Expected to finish
-
Oct 2026
An estimate. End dates often move.
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
50 to 75 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria : * Aged between 50 and 75; * Proficient or native speakers in French or English; * Computer literate defined as being able to read mails and browse the Internet, and having access to a computer or tablet with an Internet connection; * Eligible in at least one of the 3 intervention domains, where eligibility is defined as follows: * Low cognitive engagement in cognitively stimulating activities, defined as a score ≤ 22 on the adapted Cognitive Activity Questionnaire; * Low level of physical activity defined as less than 150 minutes/week) of moderate to vigorous physical activity measured using the Godin- Shephard Leisure Time Physical Activity Questionnaire, and no medical contraindication to physical activity based on the Physical Readiness Questionnaire for Everyone (PAR-Q+); * Low adherence to the Mediterranean-type diet defined as a score of ≤ 8 on the adapted Canadian Mediterranean Diet Scale, and no dietary restriction, severe allergy or intolerance or history of eating disorder. Exclusion Criteria : * Presence of a cognitive impairment as measured by the Creyos Dementia Assessment; * General anesthesia within the last 6 months; * Previous participation in the Luci program or in any validation studies related to the program; * Current participation in another study; * Unable to commit participation over the period of the study; * Being in the precontemplation stage of change; * High level of perceived stress; * Having received a diagnosis of : * Dementia or neurodegenerative disease (AD and other dementias); * Past or present neurological disorder (multiple sclerosis, brain tumour, epilepsy, stroke, traumatic brain injury); * Severe psychiatric disorder (schizophrenia, major depression, bipolar disorder); * Diabetes or hypertension without medical monitoring; * Alcoholism or drug addiction; * Any other condition expected to limit participation (e.g., low visual acuity).
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Cognitive decline are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Lucilab
Montreal, Quebec, H2T 1A8, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can brain training rewire the MS brain? study probes cognitive decline
- Can a daily supplement shield the brain after delirium?
- App-Based lifestyle coaching aims to cut dementia risk in older adults
- Can diet and lifestyle shape life after a heart attack? a large study investigates
- A text a day: could smartphone prompts curb HIV risk?
- Can we predict chemo brain before it happens?