Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New eye drug shows promise in battle against blinding disease

NCT ID NCT04690556

Disease control Sponsor: Lupin Ltd. Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new medication, LUBT010, against the standard drug Lucentis for people with wet age-related macular degeneration (AMD), a leading cause of vision loss. Six hundred participants received monthly injections into the eye for one year. The goal was to see if LUBT010 works just as well and is as safe as Lucentis in improving or maintaining eyesight.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

600 people

The number who actually took part.

Started

Sep 2020

Finished

May 2024

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Ambulatory male or female participants with age ≥ 50 years at the time of screening 2. Capable of understanding and giving written informed consent 3. Primary or recurrent (anti-vascular endothelial growth factor naïve) active choroidal neovascularization (CNV) lesions involving the foveal center secondary to AMD 4. Best corrected visual acuity (BCVA) between 20/40 and 20/200 (Snellen equivalent) in the study eye, using ETDRS testing 5. Willingness and ability to undertake all scheduled visits and assessments Exclusion Criteria: 1. Known hypersensitivity to ranibizumab or any of the components of study medication 2. Known history of allergy to fluorescein dye 3. Scar, fibrosis, or atrophy involving the center of the fovea in the study eye 4. Subretinal hemorrhage in the study eye that involves the center of the fovea 5. Uncontrolled glaucoma 6. Use of prohibited treatments Other In-/Exclusion criteria may apply

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Neovascular age-related macular degeneration are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

wet macular degeneration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Neovascular age-related macular degeneration

Contacts and locations

Locations

  • Aakash Healthcare Super Specialty Hospital

    New Delhi, 110075, India

  • Aditya Jyot Eye Hospital Pvt. Ltd.

    Mumbai, Maharashtra, 400031, India

  • Advance Retina Care

    Ahmedabad, Gujarat, 380005, India

  • Advanced Eye Centre Post Graduate Institute of Medical Education & Research

    Chandigarh, Punjab, 160012, India

  • Ambade Eye Hospital

    Nagpur, Maharashtra, 440017, India

  • Anideep Eye Hospital

    Mumbai, Maharashtra, 400056, India

  • BHI of Omsk region Clinical Ophthalmology Hospital n.a V.P. Vykhodtsev

    Omsk, 644024, Russia

  • Black Hills Regional Eye Institute

    Rapid City, South Dakota, 57701, United States

  • Bruce A. Segal, MD, PA

    Delray Beach, Florida, 33484, United States

  • CaminoMed - Specjalistyczne Gabinety Lekarskie

    Tarnowskie Góry, 42-600, Poland

  • Clinical Medical Research Sp. z o.o.

    Katowice, 40-156, Poland

  • Cumberland Valley Retina Consultants, P.C.

    Hagerstown, Maryland, 21740, United States

  • DCC Alexandrovska, EOOD

    Sofia, 1431, Bulgaria

  • Deshmukh Eye Hospital

    Amravati, Maharashtra, 444601, India

  • Dhadiwal Hospital in Coalition with Shreeji Healthcare

    Nashik, Maharashtra, 422002, India

  • Dr. D. Y. Patil Medical College

    Pune, Maharashtra, 411018, India

  • Dr. J L Rohatgi Memorial Eye Hospital

    Kanpur, Uttar Pradesh, 208005, India

  • Dr. Shroff's Charity Eye Hospital

    New Delhi, 110002, India

  • Dr.Agarwal's Eye Hospital

    Tirunelveli, Tamil Nadu, 627003, India

  • Drishtipunj Eye Hospital Pvt Ltd

    Patna, Bihar, 801503, India

  • ETG Lodz

    Lodz, 90-302, Poland

  • Eye medical center - Visus

    Gorna Oryahovitsa, 5100, Bulgaria

  • Fakultna nemocnica Trencin

    Trenčín, 91101, Slovakia

  • Fakultna nemocnica s poliklinikou F.D. Roosevelta

    Banská Bystrica, 97517, Slovakia

  • Fakultna nemocnica s poliklinikou Nove Zamky

    Nové Zámky, 94001, Slovakia

  • Fakultna nemocnica s poliklinikou Zilina

    Žilina, 01001, Slovakia

  • Gabinet Okulistyczny prof. Edward Wylegala

    Katowice, 40-594, Poland

  • Government Eye Hospital M & J Institute of Ophthalmology

    Ahmedabad, Gujarat, 380016, India

  • Gyor-Moson-Sopron Varmegyei Petz Aladar Egyetemi Oktato Korhaz

    Győr, 9024, Hungary

  • Insight Institute of Ophthalmology

    Pune, Maharashtra, 411039, India

  • JSS Hospital

    Mysore, Karnataka, 570004, India

  • Kamalnayan Bajaj Hospital

    Aurangabad, Maharashtra, 431010, India

  • Kanoria Hospital and Research Center

    Gandhinagar, Gujarat, 382428, India

  • Kashyap Memorial Eye Hospital Pvt. Ltd.

    Ranchi, Jharkhand, 834001, India

  • Kenia Eye Hospital

    Mumbai, Maharashtra, 400054, India

  • King George's Medical University

    Lucknow, Uttar Pradesh, 226003, India

  • Kiran Hospital Multi Super Speciality Hospital & Research Centre

    Surat, Gujarat, 395004, India

  • LLC HI Optic-Center

    Chelyabinsk, 454007, Russia

  • LLC X7 Clinical research

    Saint Petersburg, 194156, Russia

  • M & J Western Regional Institute of Ophthalmology

    Ahmedabad, Gujarat, 380016, India

  • MC Ophta-Nevro

    Sofia, 1172, Bulgaria

  • MHAT Trakia, EOOD

    Stara Zagora, 6000, Bulgaria

  • Medical Center Oxycom EOOD

    Burgas, 8000, Bulgaria

  • Medical Center Vereya EOOD

    Stara Zagora, 6008, Bulgaria

  • Military Medical Academy - MHAT

    Sofia, 1606, Bulgaria

  • Mysore Medical College and Research Institute

    Mysore, Karnataka, 570001, India

  • Nemocnica Poprad a.s.

    Poprad, 05801, Slovakia

  • Nemocnica s poliklinikou Trebisov a.s.

    Trebišov, 07501, Slovakia

  • Nemocnica svateho Michala

    Bratislava, 81108, Slovakia

  • Nethra Eye Hospital

    Bangalore, Karnataka, 560094, India

  • Netralaya - Super Speciality Eye Hospital

    Ahmedabad, Gujarat, 380006, India

  • P N Desai Eye Hospital

    Ahmedabad, Gujarat, 380052, India

  • Provisus Badania Kliniczne Sp. z o.o.

    Częstochowa, 42-209, Poland

  • Prywatna Klinika Okulistyczna OFTALMIKA

    Bydgoszcz, 85-631, Poland

  • R.K.Netralaya Eye Hospital (P) Ltd.

    Varanasi, Uttar Pradesh, 221010, India

  • RSHI State Novosibirsk Regional Clinical Hospital

    Novosibirsk, 630087, Russia

  • Regional Institute of Ophthalmology

    Kolkata, West Bengal, 700073, India

  • Regional Institute of Opthalmology

    Trivandrum, Kerala, 695035, India

  • Retina-Vitreous Associates Medical Group

    Beverly Hills, California, 90211, United States

  • Rising Retina Clinic

    Ahmedabad, Gujarat, 380015, India

  • Sadguru Netra Chikitsalaya

    Ahmedabad, Gujarat, 380005, India

  • Sam Eye Hospital

    Lucknow, Uttar Pradesh, Sam Eye Hospital, India

  • Shivam Retina Clinic and Eye Hospital

    Surat, Gujarat, 395001, India

  • Shroff Eye Hospital & Vision Research Centre

    Mumbai, Maharashtra, 400050, India

  • Sir Ganga Ram Hosptial

    New Delhi, 110060, India

  • Specialized Eye Hospital Pentagram

    Sofia, 1319, Bulgaria

  • Specialized Hospital for Active Treatment of Ophthalmologic Diseases Zora, OOD

    Sofia, 1784, Bulgaria

  • Specjalistyczny Osrodek Okulistyczny Oculomedica

    Bydgoszcz, 85-157, Poland

  • Sri Guru Ram Das Institute of Medical Sciences & Research

    Amritsar, Punjab, 143501, India

  • Standard Clinic Penza LLC

    Penza, 440026, Russia

  • Szpital Świętego Łukasza S. A.

    Bielsko-Biala, 43309, Poland

  • The Eye Care Center

    Guwahati, Assam, 781003, India

  • Topiwala National Medical College & B. Y. L. Nair Charitable Hospital

    Mumbai, Maharashtra, 400056, India

  • UPMC Eye Center - Eye and Ear Institute

    Pittsburgh, Pennsylvania, 15213, United States

  • University First MHAT-Sofia, St. Joan Krastitel EAD

    Sofia, 1142, Bulgaria

  • Univerzitna nemocnica Bratislava, Nemocnica Ruzinov

    Bratislava, 82601, Slovakia

  • Valley Retina Institute

    McAllen, Texas, 78503, United States

  • Vijay Vallabh Hospital and Medical Research Center

    Pālghar, Maharashtra, 401303, India

More trials for these conditions

Other studies related to the condition(s) this trial covers.