New eye drug shows promise in battle against blinding disease
NCT ID NCT04690556
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new medication, LUBT010, against the standard drug Lucentis for people with wet age-related macular degeneration (AMD), a leading cause of vision loss. Six hundred participants received monthly injections into the eye for one year. The goal was to see if LUBT010 works just as well and is as safe as Lucentis in improving or maintaining eyesight.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Aakash Healthcare Super Specialty Hospital
New Delhi, 110075, India
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Aditya Jyot Eye Hospital Pvt. Ltd.
Mumbai, Maharashtra, 400031, India
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Advance Retina Care
Ahmedabad, Gujarat, 380005, India
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Advanced Eye Centre Post Graduate Institute of Medical Education & Research
Chandigarh, Punjab, 160012, India
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Ambade Eye Hospital
Nagpur, Maharashtra, 440017, India
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Anideep Eye Hospital
Mumbai, Maharashtra, 400056, India
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BHI of Omsk region Clinical Ophthalmology Hospital n.a V.P. Vykhodtsev
Omsk, 644024, Russia
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Black Hills Regional Eye Institute
Rapid City, South Dakota, 57701, United States
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Bruce A. Segal, MD, PA
Delray Beach, Florida, 33484, United States
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CaminoMed - Specjalistyczne Gabinety Lekarskie
Tarnowskie Góry, 42-600, Poland
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Clinical Medical Research Sp. z o.o.
Katowice, 40-156, Poland
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Cumberland Valley Retina Consultants, P.C.
Hagerstown, Maryland, 21740, United States
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DCC Alexandrovska, EOOD
Sofia, 1431, Bulgaria
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Deshmukh Eye Hospital
Amravati, Maharashtra, 444601, India
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Dhadiwal Hospital in Coalition with Shreeji Healthcare
Nashik, Maharashtra, 422002, India
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Dr. D. Y. Patil Medical College
Pune, Maharashtra, 411018, India
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Dr. J L Rohatgi Memorial Eye Hospital
Kanpur, Uttar Pradesh, 208005, India
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Dr. Shroff's Charity Eye Hospital
New Delhi, 110002, India
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Dr.Agarwal's Eye Hospital
Tirunelveli, Tamil Nadu, 627003, India
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Drishtipunj Eye Hospital Pvt Ltd
Patna, Bihar, 801503, India
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ETG Lodz
Lodz, 90-302, Poland
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Eye medical center - Visus
Gorna Oryahovitsa, 5100, Bulgaria
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Fakultna nemocnica Trencin
Trenčín, 91101, Slovakia
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Fakultna nemocnica s poliklinikou F.D. Roosevelta
Banská Bystrica, 97517, Slovakia
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Fakultna nemocnica s poliklinikou Nove Zamky
Nové Zámky, 94001, Slovakia
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Fakultna nemocnica s poliklinikou Zilina
Žilina, 01001, Slovakia
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Gabinet Okulistyczny prof. Edward Wylegala
Katowice, 40-594, Poland
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Government Eye Hospital M & J Institute of Ophthalmology
Ahmedabad, Gujarat, 380016, India
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Gyor-Moson-Sopron Varmegyei Petz Aladar Egyetemi Oktato Korhaz
Győr, 9024, Hungary
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Insight Institute of Ophthalmology
Pune, Maharashtra, 411039, India
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JSS Hospital
Mysore, Karnataka, 570004, India
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Kamalnayan Bajaj Hospital
Aurangabad, Maharashtra, 431010, India
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Kanoria Hospital and Research Center
Gandhinagar, Gujarat, 382428, India
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Kashyap Memorial Eye Hospital Pvt. Ltd.
Ranchi, Jharkhand, 834001, India
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Kenia Eye Hospital
Mumbai, Maharashtra, 400054, India
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King George's Medical University
Lucknow, Uttar Pradesh, 226003, India
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Kiran Hospital Multi Super Speciality Hospital & Research Centre
Surat, Gujarat, 395004, India
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LLC HI Optic-Center
Chelyabinsk, 454007, Russia
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LLC X7 Clinical research
Saint Petersburg, 194156, Russia
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M & J Western Regional Institute of Ophthalmology
Ahmedabad, Gujarat, 380016, India
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MC Ophta-Nevro
Sofia, 1172, Bulgaria
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MHAT Trakia, EOOD
Stara Zagora, 6000, Bulgaria
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Medical Center Oxycom EOOD
Burgas, 8000, Bulgaria
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Medical Center Vereya EOOD
Stara Zagora, 6008, Bulgaria
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Military Medical Academy - MHAT
Sofia, 1606, Bulgaria
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Mysore Medical College and Research Institute
Mysore, Karnataka, 570001, India
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Nemocnica Poprad a.s.
Poprad, 05801, Slovakia
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Nemocnica s poliklinikou Trebisov a.s.
Trebišov, 07501, Slovakia
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Nemocnica svateho Michala
Bratislava, 81108, Slovakia
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Nethra Eye Hospital
Bangalore, Karnataka, 560094, India
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Netralaya - Super Speciality Eye Hospital
Ahmedabad, Gujarat, 380006, India
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P N Desai Eye Hospital
Ahmedabad, Gujarat, 380052, India
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Provisus Badania Kliniczne Sp. z o.o.
Częstochowa, 42-209, Poland
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Prywatna Klinika Okulistyczna OFTALMIKA
Bydgoszcz, 85-631, Poland
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R.K.Netralaya Eye Hospital (P) Ltd.
Varanasi, Uttar Pradesh, 221010, India
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RSHI State Novosibirsk Regional Clinical Hospital
Novosibirsk, 630087, Russia
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Regional Institute of Ophthalmology
Kolkata, West Bengal, 700073, India
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Regional Institute of Opthalmology
Trivandrum, Kerala, 695035, India
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Retina-Vitreous Associates Medical Group
Beverly Hills, California, 90211, United States
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Rising Retina Clinic
Ahmedabad, Gujarat, 380015, India
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Sadguru Netra Chikitsalaya
Ahmedabad, Gujarat, 380005, India
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Sam Eye Hospital
Lucknow, Uttar Pradesh, Sam Eye Hospital, India
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Shivam Retina Clinic and Eye Hospital
Surat, Gujarat, 395001, India
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Shroff Eye Hospital & Vision Research Centre
Mumbai, Maharashtra, 400050, India
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Sir Ganga Ram Hosptial
New Delhi, 110060, India
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Specialized Eye Hospital Pentagram
Sofia, 1319, Bulgaria
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Specialized Hospital for Active Treatment of Ophthalmologic Diseases Zora, OOD
Sofia, 1784, Bulgaria
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Specjalistyczny Osrodek Okulistyczny Oculomedica
Bydgoszcz, 85-157, Poland
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Sri Guru Ram Das Institute of Medical Sciences & Research
Amritsar, Punjab, 143501, India
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Standard Clinic Penza LLC
Penza, 440026, Russia
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Szpital Świętego Łukasza S. A.
Bielsko-Biala, 43309, Poland
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The Eye Care Center
Guwahati, Assam, 781003, India
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Topiwala National Medical College & B. Y. L. Nair Charitable Hospital
Mumbai, Maharashtra, 400056, India
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UPMC Eye Center - Eye and Ear Institute
Pittsburgh, Pennsylvania, 15213, United States
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University First MHAT-Sofia, St. Joan Krastitel EAD
Sofia, 1142, Bulgaria
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Univerzitna nemocnica Bratislava, Nemocnica Ruzinov
Bratislava, 82601, Slovakia
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Valley Retina Institute
McAllen, Texas, 78503, United States
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Vijay Vallabh Hospital and Medical Research Center
Pālghar, Maharashtra, 401303, India
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Longer-Lasting eye injection could cut treatment visits for macular disease
- Can a new eye injection save vision in wet AMD?
- Eye injection aims to tame leading causes of blindness
- Higher-Dose eye injection may help wet AMD patients who Didn't respond to standard treatments
- New eye drug aims to save sight in wet AMD
- Withdrawn study sought better way to time eye injections