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New pill targets hard-to-treat cancers with KRAS G12D mutation

NCT ID NCT07624214

First seen Jun 10, 2026 · Last updated Jun 10, 2026

Summary

This early-stage study tests a new tablet, LT-010391, in people with advanced solid tumors (lung, colon, or pancreatic cancer) that have a specific genetic change called KRAS G12D. The main goals are to check safety and find the right dose. About 198 participants who have tried other treatments without success will take the drug and be monitored for side effects and tumor shrinkage.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Zhejiang Cancer Hospital

    Hangzhou, Zhejiang, 310022, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

The condition(s) this trial relates to.

Carcinoma, Non-Small-Cell Lung Colorectal Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.