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Gentler gas pressure may ease Kids' pain after appendix surgery

NCT ID NCT04949659

Symptom relief Sponsor: University Children's Hospital, Zurich Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 2 times

Summary

This study looked at 250 children having laparoscopic surgery for appendicitis. It compared using low versus medium gas pressure in the belly during the operation to see if it affects pain the next day. The goal is to find ways to make children more comfortable after surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

250 people

The number who actually took part.

Started

Sep 2021

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

5 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Prepped and consented for diagnostic laparoscopy for likely acute appendicitis * 5 years or older * 15 kg or more * Parents/legal custodian give consent, patient shows no signs of unwillingness to participate * Patient is hemodynamically stable Exclusion Criteria: * Clinical signs of four quadrant peritonitis as a clinical sign of perforated appendicitis * Suspected perityphlitic abscess on preoperative ultrasound * Preexisting conditions making postoperative assessment of extent of pain and its localization very difficult or impossible, e.g. conditions that are associated with pronounced developmental delays or with communication difficulties * Parents have inadequate knowledge of German language to understand Informed consent * Child has inadequate knowledge of German language to allow elicitation of Pain Scores

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Conditions

The condition(s) this trial relates to.

appendicitis Pain Pneumoperitoneum

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Appendicitis acute

Contacts and locations

Locations

  • University Children's Hospital Zurich

    Zurich, Canton of Zurich, 8032, Switzerland

More trials for these conditions

Other studies related to the condition(s) this trial covers.