Appendicitis acute

This study tests whether a simple checklist plus a finger-prick blood test can help family doctors decide which children with belly pain need to go to the hospital for possible appendicitis. About 566 children aged 4 to 18 will take part. If it works, fewer kids without appendici…

This study is testing a new blood test that looks at RNA (genetic material) to quickly tell if a person with belly pain has an infection inside the abdomen, like appendicitis or diverticulitis. About 1,000 adults and children over age 7 with abdominal pain will give a blood sampl…

Researchers test whether the location used to pull out the appendix (near the belly button versus the lower left abdomen) and numbing medicine injected into the small incisions change pain after laparoscopic appendectomy. Adults with acute appendicitis having emergency surgery jo…

This study compares two ways of adjusting the air cushion (cuff) on the breathing tube used during general anesthesia in children having laparoscopic appendectomy. One group uses the standard finger-palpation method, while the other uses a pressure sensor to keep the cuff within …

This study tests whether patients with gangrenous appendicitis can safely go home shortly after emergency laparoscopic surgery instead of staying in the hospital. About 122 adults will be enrolled to compare safety, recovery, and costs. The goal is to see if outpatient management…

This pilot study tests whether a tool called ClassIntra, used to grade unexpected events during surgery, can be applied to children having their appendix removed. Researchers will record the operations of 80 children aged 5 to 17 and have two independent surgeons review the video…

This study tests whether Fitbit data (like heart rate and activity) can help predict infections in children recovering from complicated appendectomy. Researchers will develop an algorithm and see if it helps doctors make decisions. 500 children aged 3-18 are being enrolled.

This study looks at how a common bowel-cleansing drink (PEG) used before colonoscopy changes the gut bacteria in people who have had their appendix removed. Researchers will compare these changes to those in people with an intact appendix. The goal is to understand if the appendi…