Can a quick workout help heart failure patients?
NCT ID NCT07325942
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether shorter or longer sessions of high-intensity interval training (HIIT) work better for people with chronic heart failure. Researchers will measure changes in walking ability, heart function, and quality of life in 45 participants. The goal is to find a time-efficient exercise option that still provides real benefits.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- high-intensity interval training (HIIT)
- What this could lead to
- If successful, this could show that shorter, time-efficient exercise sessions are just as effective as longer ones for heart failure patients, making it easier to fit into daily life.
- What could go wrong
- This is a small, early-phase study with only 45 participants, so results may not apply to all heart failure patients. Exercise programs also require ongoing commitment and may not be suitable for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 45 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Chronic stable heart failure patient with reduced ejection fraction (EF \<40) 2. Age Above 18 years old 3. Both males and females 4. The ability to provide informed consent Exclusion Criteria: 1. Based on the Scientific Statement from the American Heart Association: contraindications for exercise Testing and Training. (Fletcher et al., 2013) 1. Acute myocardial infarction (MI), within 2 days 2. Ongoing unstable angina 3. Uncontrolled cardiac tachy or brady arrhythmia with hemodynamic compromise 4. Active endocarditis 5. Symptomatic severe aortic stenosis 6. Decompensated heart failure 7. Acute pulmonary embolism, pulmonary infarction, or deep vein thrombosis 8. Acute myocarditis or pericarditis 9. Acute aortic dissection 10. Physical disability that precludes safe and adequate testing or training 11. Known obstructive left main coronary artery stenosis 12. Hypertrophic obstructive cardiomyopathy with severe resting gradient 13. Recent stroke or transient ischemic attack 14. Mental impairment with limited ability to cooperate 15. Resting hypertension with systolic or diastolic blood pressures \>200/110 mmHg 16. Uncorrected medical conditions, such as significant anemia, important electrolyte imbalance, and hyperthyroidism 2. Acute decompensated heart failure NYHA class IV
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Cairo University
RECRUITINGCairo, Giza Governorate, Egypt
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