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Can a higher dose of labor drug shorten delivery time?

NCT ID NCT05782816

Symptom relief Sponsor: The University of Texas Medical Branch, Galveston Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a higher starting dose of oxytocin (a drug used to start or speed up labor) could shorten the time from induction to delivery in first-time mothers. 170 women were randomly assigned to receive either a low or high dose. Researchers also looked at whether the dose affected the type of delivery (vaginal or C-section) and the health of both mother and baby.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

170 people

The number who actually took part.

Started

Apr 2023

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women aged 18-50 years old * Singleton gestation * Nulliparous * Vertex presentation * Gestational age greater than or equal to 37 weeks * No prior uterine surgery * Presents for elective or medically indicated induction of labor * Need for augmentation of labor with oxytocin Exclusion Criteria: * Previous cervical ripening using non-mechanical methods * Patient unable or unwilling to provide verbal consent * Contraindications to vaginal delivery * Fetal demise or life-limiting anomaly * Allergy to oxytocin * Non-reassuring fetal heart tracing prior to inclusion * Maternal pulmonary edema prior to inclusion * Fetal growth restriction

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Labor long

Contacts and locations

Locations

  • University of Texas Medical Branch

    Galveston, Texas, 77555, United States