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Can cutting calories or boosting exercise reveal hidden energy crisis in athletes?

NCT ID NCT07026175

Knowledge-focused Sponsor: Australian Catholic University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This trial investigates how the body responds to short-term, severe low energy availability (LEA) in healthy endurance athletes aged 18-45. LEA occurs when energy intake is too low for training demands. Researchers will compare a control condition with two LEA conditions—one from diet restriction and one from increased exercise—to see how sleeping metabolic rate and other body systems are affected. Participants will complete three 6-day trials, including stays in a metabolic chamber, to measure these responses.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Diet-induced low energy availability and exercise-induced low energy availability
What this could lead to
If successful, this could improve understanding of how low energy availability affects athletes' health and performance, potentially guiding better prevention and management strategies for Relative Energy Deficiency in Sport.
What could go wrong
This is a small, early-stage study with only 20 participants, so findings may not apply to all athletes. The short-term nature of the intervention may not reflect long-term effects, and there are risks of discomfort from severe calorie restriction and increased exercise.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18-45 years old * Well trained weight-bearing athlete (tier 2-4 1) * Perform \~45km per week of weight-bearing endurance training, and able to undertake the prescribed exercise in each trial condition * Pass the ESSA pre-exercise screening tool and/or obtain GP clearance to exercise Exclusion Criteria: * Assessment of red status on the REDs Clinical Assessment Tool * Unable to attend ACU in Fitzroy, Victoria, for the 6 study visits for completion of the study protocol * Pregnancy * Use of hormonal contraceptive with the previous 3 months * Onset of peri/menopause

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Conditions

The condition(s) this trial relates to.

Relative Energy Deficiency in Sport

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Relative energy deficiency in sport

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Australian Catholic University

    RECRUITING

    Fitzroy, Victoria, 3065, Australia

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