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Could a tiny dose of an alcohol addiction drug ease vasculitis symptoms?

NCT ID NCT03482479

First seen Jan 23, 2026 · Last updated Jun 01, 2026 · Updated 24 times

Summary

This study tested whether a low dose of naltrexone, a drug normally used for alcohol dependence, can improve physical health and quality of life in people with vasculitis (a group of rare blood vessel diseases). Sixty adults with different types of vasculitis took either the low dose drug or a placebo. The goal was to see if the drug could reduce symptoms like pain and fatigue better than a placebo.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • St. Joseph's Healthcare

    Hamilton, Ontario, Canada

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15260, United States

  • University of Utah

    Salt Lake City, Utah, 84112, United States

Conditions

The condition(s) this trial relates to.

eosinophilic granulomatosis with polyangiitis Giant Cell Arteritis granulomatosis with polyangiitis microscopic polyangiitis polyarteritis nodosa Takayasu arteritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.