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Can a tiny dose of IL-2 tame hay fever? new trial explores

NCT ID NCT03776643

First seen Nov 01, 2025 · Last updated Jun 15, 2026 · Updated 36 times

Summary

This study tested whether a low dose of IL-2, a protein that helps calm the immune system, could reduce nasal symptoms in people with birch pollen allergy. Twenty-four adults with a history of seasonal hay fever received either the drug or a placebo and were then exposed to birch pollen in a controlled chamber. The main goal was to see if the treatment eased nasal congestion during exposure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CIC Biothérapies - Service de Biothérapies

    Paris, Groupe Hospitalier Pitié-Salpêtrière 47 -83 BD de L'hopital, 75013, France

  • Centre d'essais cliniques, ALYATEC

    Strasbourg, Environmental Exposure Chamber, Alyatec, 1 Place de L'hôpital, 67000, France

Conditions

The condition(s) this trial relates to.

seasonal allergic rhinitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.