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Could a tiny dose of esketamine lift post-surgery depression in obese patients?

NCT ID NCT07179913

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 24 times

Summary

This study looks at whether giving a small amount of esketamine during and after weight-loss surgery can help reduce depression in obese patients who already feel depressed before surgery. About 40 adults with a BMI over 35 and a Hamilton Depression score of 7 or higher will take part. The goal is to see if this approach lowers the number of people who remain depressed after surgery and improves their recovery and quality of life.

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Contacts and locations

Locations

  • Zhiwen Li

    Changchun, Jilin, 130021, China

Conditions

Explore the condition pages connected to this study.