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New wearable device could help brain surgeons remove tumors more completely

NCT ID NCT04780009

First seen Jun 09, 2026 · Last updated Jun 23, 2026 · Updated 4 times

Summary

This study tests a special pair of magnifying glasses (loupes) that help surgeons see glowing brain tumor tissue during surgery. The device uses a fluorescent dye to make tumor cells light up, so the surgeon can remove more of the tumor while sparing healthy brain. The trial will compare the loupes to a standard large microscope to see if they are just as accurate. Thirty adults with glioblastoma or anaplastic astrocytoma will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Kentucky

    RECRUITING

    Lexington, Kentucky, 40536, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

fluorescent imaging agent (likely 5-ALA or similar)

What this could lead to

If successful, this could provide a low-cost, portable tool to help surgeons remove more tumor tissue during brain surgery, potentially improving patient outcomes.

What could go wrong

This is a small early-stage study (30 participants) focused on accuracy, not survival. The device may not prove better than existing methods, and results may not apply to all brain tumor types.

Conditions

The condition(s) this trial relates to.

anaplastic astrocytoma Astrocytoma glioblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.