Could a common painkiller boost brain development in preemies?
NCT ID NCT06064825
First seen Apr 20, 2026 · Last updated Jun 23, 2026 · Updated 12 times
Summary
This study follows 500 extremely preterm infants who received paracetamol or placebo in the TREOCAPA trial. Researchers will use a parent questionnaire to assess cognitive development at age 2. The goal is to see if early paracetamol use improves thinking and learning skills in these vulnerable children.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Locations
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CHU d'Angers
RECRUITINGAngers, France
Contact
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CHU de Montpellier
RECRUITINGMontpellier, France
Contact
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CHU de Nantes
RECRUITINGNantes, France
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CHU de Strasbourg
RECRUITINGStrasbourg, France
Contact
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CHU de Tours
RECRUITINGTours, France
Contact
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Cochin - APHP
RECRUITINGParis, France
Contact
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Hopital Robert Debré
RECRUITINGParis, France
Contact
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Hôpital Femme Mère Enfant
RECRUITINGBron, France
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
paracetamol (acetaminophen)
What this could lead to
If successful, this could show that early paracetamol treatment helps prevent cognitive delays in extremely preterm infants.
What could go wrong
This is a follow-up study, not a new treatment trial. Results depend on parent reports, which may not be fully accurate, and the original trial may not show a clear benefit.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.