Could a common painkiller boost brain development in preemies?

NCT ID NCT06064825

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 500 extremely preterm infants who received paracetamol or placebo in the TREOCAPA trial. Researchers will use a parent questionnaire to assess cognitive development at age 2. The goal is to see if early paracetamol use improves thinking and learning skills in these vulnerable children.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
paracetamol (acetaminophen)
What this could lead to
If successful, this could show that early paracetamol treatment helps prevent cognitive delays in extremely preterm infants.
What could go wrong
This is a follow-up study, not a new treatment trial. Results depend on parent reports, which may not be fully accurate, and the original trial may not show a clear benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU d'Angers

    RECRUITING

    Angers, France

  • CHU de Montpellier

    RECRUITING

    Montpellier, France

  • CHU de Nantes

    RECRUITING

    Nantes, France

  • CHU de Strasbourg

    RECRUITING

    Strasbourg, France

  • CHU de Tours

    RECRUITING

    Tours, France

  • Cochin - APHP

    RECRUITING

    Paris, France

  • Hopital Robert Debré

    RECRUITING

    Paris, France

  • Hôpital Femme Mère Enfant

    RECRUITING

    Bron, France