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Can a cure for sickle cell disease harm the heart, lungs, or kidneys?

NCT ID NCT05153967

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 24 times

Summary

This study follows 750 people with sickle cell disease to see if curative treatments (like stem cell transplants) improve or worsen heart, lung, and kidney function compared to standard therapy. Researchers will also look for genetic clues that predict good or bad outcomes. The goal is to help patients and doctors make better treatment choices.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's National Medical Center

    NOT_YET_RECRUITING

    Washington D.C., District of Columbia, 20010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Emory University School of Medicine

    NOT_YET_RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Johns Hopkins Hospital

    NOT_YET_RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • National Institutes of Health Clinical Center

    NOT_YET_RECRUITING

    Bethesda, Maryland, 20814, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232-9000, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.