Heart valve mismatch mystery: does it really matter after surgery?
NCT ID NCT00854698
First seen Nov 01, 2025 · Last updated Jun 20, 2026 · Updated 38 times
Summary
This study followed 77 patients under 60 who had a mechanical aortic valve replacement to see if a mismatch between the valve size and the patient's body affects heart recovery and exercise ability. Participants did exercise tests and heart ultrasounds years after surgery. The goal is to settle a debate about whether valve mismatch truly impacts long-term heart function and quality of life.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHRU, Nouvel Hôpital Civil, Service de chirurgie cardio-vasculaire
Strasbourg, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
exercise training
What this could lead to
If successful, this could clarify whether aortic valve mismatch after replacement truly limits exercise capacity and heart recovery, guiding future treatment decisions.
What could go wrong
This is a small, completed observational study with only 77 participants, so results may not apply to all patients. It does not test a new treatment, so no direct benefit is expected.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.