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Pregnancy blood clot risk: are current doses right?

NCT ID NCT01394107

Knowledge-focused Sponsor: Charles University, Czech Republic Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study checked how a standard dose of a blood thinner (LMWH) affects clotting in 40 pregnant women just before a planned C-section. The goal was to see if the dose is safe and effective for preventing dangerous blood clots, which are a leading cause of death in new mothers. Researchers used advanced tests to measure clotting over 24 hours and to assess the risk of spinal bleeding during anesthesia.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Low molecular weight heparin (LMWH)
What this could lead to
If successful, this could help doctors determine the right blood-thinner dose for pregnant women, reducing clot risks without increasing bleeding danger.
What could go wrong
This is a small pilot study with only 40 participants, so results may not apply to all pregnant women. The findings are observational and need confirmation in larger trials.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

40 people

The number who actually took part.

Started

Jan 2021

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

pregnant women undergoing planned caesarean section, 39th-40th week of pregnancy, age 18-40 years

Ages

18 to 40 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * pregnant women undergoing planned caesarean section * 39th-40th week of pregnancy * age 18-40 years Exclusion Criteria: * disapproval or non-cooperation of the mother * allergy to LMWH * coagulation disorders or the risk of * anticoagulant therapy in the last 3 months * signs of infection * history of cancer * signs of thrombosis or a history of thrombosis * the ongoing non-physiological pregnancy * significant obesity, or other severe comorbidity

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pregnancy

Contacts and locations

Locations

  • General University Hospital in Prague

    Prague, 128 08, Czechia

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