Scientists test if damaged livers change cancer drug effects

NCT ID NCT04241835

Recruiting now Knowledge-focused Sponsor: Epizyme, Inc. Source: ClinicalTrials.gov ↗

Summary

This early study aims to understand how liver problems affect the way the body processes a cancer drug called tazemetostat. It will compare blood levels of the drug in people with advanced cancer who have normal liver function to those with moderate or severe liver impairment. The study will also check the drug's safety in these participants.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Antwerp University Hospital
TERMINATED

Edegem, Antwerp, 2650, Belgium
Biokinetica S.A Przychodnia Jozefow
WITHDRAWN

Józefów, Masovian Voivodeship, 05410, Poland
Centre Oscar Lambret
TERMINATED

Lille, 59020, France
Cliniques Universitaires Saint-Luc
WITHDRAWN

Brussels, 1200, Belgium
Comprehensive Cancer Center of Nevada
COMPLETED

Las Vegas, Nevada, 89014, United States
Florida Cancer Specialists & Research Institute
COMPLETED

Lake Mary, Florida, 32746, United States
Gabrail Cancer Center
COMPLETED

Canton, Ohio, 44718, United States
Hematology Oncology Consultants
COMPLETED

Royal Oak, Michigan, 48073, United States
Hopital de la Timone
WITHDRAWN

Marseille, 13005, France
Institut Bergonie
TERMINATED

Bordeaux, 33076, France
Institut de Cancérologie Strasbourg Europe
TERMINATED

Strasbourg, France
Mary Crowley Cancer Research
COMPLETED

Dallas, Texas, 75230, United States
MedPolonia
TERMINATED

Poznan, Greater Poland Voivodeship, 60693, Poland
Oncology Consultants - Texas Medical Center
WITHDRAWN

Houston, Texas, 77030, United States
Robert H. Lurie Comprehensive Cancer Center of Northwestern University
COMPLETED

Chicago, Illinois, 60611, United States
Rutgers Cancer Institute
RECRUITING

New Brunswick, New Jersey, 08901, United States
Summit Clinical Research, s.r.o
TERMINATED

Bratislava, 831 01, Slovakia
Virginia Cancer Specialists
RECRUITING

Fairfax, Virginia, 22031, United States

Conditions

Explore the condition pages connected to this study.

ADVANCED MALIGNANT SOLID TUMOR HEPATIC IMPAIRMENT