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Radiation plus immunotherapy shows promise for advanced liver cancer

NCT ID NCT05377034

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 25 times

Summary

This study tests if adding immunotherapy drugs (atezolizumab and bevacizumab) after targeted radiation therapy (SIRT-Y90) works better than radiation alone for people with advanced liver cancer that hasn't spread outside the liver. About 100 participants will be randomly assigned to receive either the drug combination or a placebo after radiation. The main goal is to see if the combination shrinks tumors more effectively over 9 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Tsinghua Changgung Hospital

    RECRUITING

    Beijing, China

  • Kaohsiung Chang Gung Memorial Hospital

    RECRUITING

    Kaohsiung City, Taiwan

  • National Cancer Centre Singapore

    RECRUITING

    Singapore, 168583, Singapore

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • National Taiwan University Cancer Center

    RECRUITING

    Taipei, Taiwan

  • National Taiwan University Hospital

    RECRUITING

    Taipei, Taiwan

  • National University Hospital

    RECRUITING

    Singapore, 119074, Singapore

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • People's Liberation Army General Hospital (1st and 6th Medical Centre)

    NOT_YET_RECRUITING

    Beijing, China

  • Samsung Medical Center

    RECRUITING

    Seoul, South Korea

  • Seoul National University Hospital

    RECRUITING

    Seoul, South Korea

  • Severance Hospital Yonsei University Health System

    RECRUITING

    Seoul, South Korea

  • Shandong Cancer Hospital

    NOT_YET_RECRUITING

    Jinan, China

  • Taichung Veterans General Hospital

    RECRUITING

    Taichung, Taiwan

  • Taipei Veterans General Hospital

    RECRUITING

    Taipei, Taiwan

  • West China Hospital, Sichuan University

    RECRUITING

    Chengdu, China

Conditions

Explore the condition pages connected to this study.