Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New jaw therapy targets the Brain's emotion center to ease pain

NCT ID NCT07392671

Symptom relief Sponsor: Hacettepe University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding a special manual therapy that targets the limbic system (the brain's emotion center) to standard physiotherapy can improve pain, jaw movement, balance, and quality of life in people with temporomandibular joint disorder (TMD). Sixty adults with TMD for at least six months took part. The treatment lasted six weeks and included hands-on techniques and exercises. The goal was to see if this combined approach works better than standard care alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
manual therapy (limbic-oriented combined with conventional physiotherapy)
What this could lead to
If it works, this could offer a more effective, non-drug treatment for jaw pain and related issues like poor balance and sleep.
What could go wrong
This is a small, completed study with only 60 participants, so results may not apply to everyone. The added benefit of the limbic-focused technique over standard therapy is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Dec 2023

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Aged between 18 and 60 years Diagnosed with temporomandibular joint dysfunction (TMD - disc displacement or degenerative joint disease) by an Oral and Maxillofacial Surgery specialist Clinical findings consistent with temporomandibular joint dysfunction Presence of symptoms and pain related to TMD for at least 6 months No history of acute trauma, infection, or neurological disease No limitation of joint range of motion in the angles assessed for joint position sense No history of any treatment or physiotherapy for TMD within the last 6 months Not using occlusal splints, orthodontic appliances, and/or medications for pain Use of no more than one fixed prosthetic restoration (bridge or implant-supported crown) in a single region Voluntary participation and provision of written informed consent Exclusion Criteria: History of jaw and/or cervical region surgery or trauma within the last 6 months Presence of rheumatological or psychiatric disorders History of fracture involving the temporomandibular joint, cervical, or upper thoracic region Presence of acute cervical disc pathology or other acute conditions affecting the cervical region Presence of skin infection or open wounds Presence of perceptual or communication disorders Partial edentulism classified as Kennedy Class I, II, or III, or multiple missing teeth that impair masticatory function, except for single-tooth loss Presence of fixed prosthetic restorations for more than one missing tooth Use of removable partial or complete dentures Unwillingness to participate in the study

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Temporomandibular disorders (TMDS) are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Pain temporomandibular joint disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Temporomandibular disorders (TMDS)

Contacts and locations

Locations

  • Hacettepe University Faculty of Physical Therapy and Rehabilitation, Musculoskeletal Physiotherapy and Rehabilitation Unit

    Ankara, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.