Light beams to calm the brain: new trial tests stress relief for epilepsy
NCT ID NCT07509177
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether shining low-level infrared light on the scalp (photobiomodulation) can lower stress and improve seizure control in people with epilepsy. Eighty adults with epilepsy will attend 45 sessions over 15 weeks. Researchers will measure changes in perceived stress and seizure patterns.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- photobiomodulation (low-level light therapy)
- What this could lead to
- If it works, this could offer a non-invasive way to reduce stress and possibly seizure frequency in people with epilepsy.
- What could go wrong
- This is an early study with no control group, so results may be due to placebo. The effect on seizures is uncertain, and the time commitment is high.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2025
- Expected to finish
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Aug 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * • \>18 YO * Epilepsy - medical diagnosis with at least one seizure within the past 6 months: diagnosis to be obtained from medical records from the treating physician by signature of HIPAA-compliant medical release form * Agreement to maintain or reduce medication regimen (based upon prescribers' advice) * Available for intake, baseline, post-treatment, 6-month follow-up assessments, and 45 sessions of PBM * Willingness to wear an Õura ring at all times (except for charging) for the duration of the study. Exclusion: * \< 17 YO * Substance use * Personality disorders * Heavy metal toxicity * Mold toxicity * Metabolic measures thresholded based on participant type * Increase in current medication (dosage and/or type) * No new medications prescribed (reduction as prescribed by prescribing physician OK) * Current brain bleed * Acute TBI within the last 12 months * History of neuromodulation, including ECT * Brain implants/pumps/shunts * History of brain surgery * Hormone replacement therapy for menopause or gender transition * Untreated sleep disorders Exclusion Criteria: \-
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
4 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Brain Health Center Miami
RECRUITINGNorth Miami, Florida, 33162, United States
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Holly Maggiano, MD
RECRUITINGWarren, Ohio, 44484, United States
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Houston Neuroscience Brain Center
RECRUITINGHouston, Texas, 77098, United States
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Right Mind Wellness Center
RECRUITINGCincinnati, Ohio, 45227, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can lavender and lullabies help kids with epilepsy sleep better?
- Reading the Brain's signals to predict who benefits from deep brain stimulation
- Can a Comfort-Focused education program improve life with epilepsy?
- Can video games rewire young brains after injury?
- High-Fat Diet's effect on epilepsy: scientists track brain signals
- Epilepsy drug candidate put to the test in healthy volunteers