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Could a simple infusion ease pain after appendix surgery?

NCT ID NCT07678385

Symptom relief Sponsor: Hospital Universitario de Caracas Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This trial investigates whether giving lidocaine through a vein during laparoscopic appendectomy can reduce pain and speed up recovery after surgery. The study includes adults aged 18 to 45 who are scheduled for this procedure. Participants receive either lidocaine or a placebo (saline) infusion, and researchers measure pain levels, opioid use, nausea, bowel function recovery, and hospital stay length.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
lidocaine
What this could lead to
If it works, this could provide a simple, low-cost way to reduce pain and opioid use after laparoscopic appendectomy.
What could go wrong
This is a single-center trial with a moderate number of participants. Lidocaine may not significantly improve pain or recovery, and there is a small risk of side effects like dizziness or heart rhythm changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

225 people

The number who actually took part.

Started

Feb 2024

Finished

Jan 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 to 45 years. * ASA physical status I or II. * Scheduled for laparoscopic appendectomy under general anesthesia. * Able to provide written informed consent. Exclusion Criteria: * History of cardiac conduction disorders or documented arrhythmias. * Hepatic insufficiency. * Renal insufficiency. * Chronic or long-term opioid therapy. * Known or suspected hypersensitivity to amide-type local anesthetics. * Hemodynamic instability at the time of admission to the operating room. * Body mass index greater than 35 kg/m².

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Laparoscopic appendectomy Post operative pain, acute

Contacts and locations

Locations

  • Hospital Universitario de Caracas

    Caracas, Miranda, 1040, Venezuela

More trials for these conditions

Other studies related to the condition(s) this trial covers.